Addison's disease and thyrotoxicosis presenting simultaneously.

orthostatic hypotension . Thyrotoxicosis presenting as

Introduction Orthostatic hypotension is a relatively common symptom caused by a variety of aetiologies. The most common of these are: neuropathies due to systemic diseases such as diabetes, amyloidosis and porphyria; vaso-vagal attacks; hypovolaemia; ShyDrager syndrome (idiopathic orthostatic hypotension); adverse effects of anti-adrenergic drugs, L-dopa and dopaminergic drugs; phaeochromocytom...

Co-existence of Addison's disease and thyrotoxicosis.

Clinical presentation of thyroid dysfunction and Addison's disease in young adults with type 1 diabetes.

In a clinic population of 509 type 1 diabetic patients aged 16-45 years, 5.5% had received treatment for thyroid disorders (20 hypothyroid, three males; eight thyrotoxicosis, four males), and Addison's disease was present in four patients (0.8%, one male). In all patients, type 1 diabetes preceded the diagnosis of the other autoimmune disorder. The clinical presentation of hypothyroidism was us...

New onset type 1 diabetes presenting as ketoacidosis simultaneously presenting with autoimmune hyperthyroidism--a case report.

Autoimmune conditions are common with an estimated prevalence in the UK of 2.5%. The presence of one condition should always prompt the clinician to look for others if new symptoms arise. Autoimmune polyglandular syndromes are well described. However, it is unusual for two or more autoimmune conditions to present simultaneously. We describe a case of two autoimmune conditions--type 1 diabetes a...

Hypercalcaemia and hypokalaemia in tuberculosis.

In two patients with extensive pulmonary tuberculosis who developed hypercalcaemia and hypokalaemia the hypercalcaemia appeared related to the use of small doses of vitamin D, which suggested patients with tuberculosis were hypersensitive to vitamin D. They were thus similar to patients with sarcoidosis, and it is interesting that the Kveim test result was positive in both cases. The hypercalca...